Quantifying mechanisms in neurodegenerative diseases (NDDs) using candidate mechanism perturbation amplitude (CMPA) algorithm

Quantifying mechanisms in neurodegenerative diseases (NDDs) using candidate mechanism perturbation amplitude (CMPA) algorithm

Abstract Background Literature derived knowledge assemblies have been used as an effective way of representing biological phenomenon and understanding disease etiology in systems biology. These include canonical pathway databases such as KEGG, Reactome and WikiPathways and disease specific network i...

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Bibliographic Details
Main Authors: Reagon Karki, Alpha Tom Kodamullil, Charles Tapley Hoyt, Martin Hofmann-Apitius
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Bioinformatics
Subjects:
Alzheimer’s disease
Parkinson’s disease
Mitochondrial dysfunction
Aggregation of neurofibrillary tangles
OpenBEL
Online Access:http://link.springer.com/article/10.1186/s12859-019-3101-1

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http://link.springer.com/article/10.1186/s12859-019-3101-1

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