Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells

Silencing of NAMPT leads to up-regulation of insulin receptor substrate 1 gene expression in U87 glioma cells

Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related proteins in U87 glioma cells for evaluation of the...

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Bibliographic Details
Main Authors: Tsymbal Daria O., Minchenko Dmytro O., Luzina Olena Y., Riabovol Olena O., Danilovskyi Serhiy V., Minchenko Oleksandr H.
Format: Article
Language:English
Published: Sciendo 2020-01-01
Series:Endocrine Regulations
Subjects:
silencing nampt
mrna expression
irs1
igfbp3
per2
clu
bnip3
tpd52
gadd45a
u87 glioma cells
Online Access:https://doi.org/10.2478/enr-2020-0005

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