Dissecting lung development and fibrosis at single-cell resolution

Editorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to inte...

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Main Authors: Donna L. Farber, Peter A. Sims
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Genome Medicine
Online Access:http://link.springer.com/article/10.1186/s13073-019-0645-7
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spelling doaj-05f96fe26db84761b7633f52a90de39d2020-11-25T02:57:25ZengBMCGenome Medicine1756-994X2019-05-011111310.1186/s13073-019-0645-7Dissecting lung development and fibrosis at single-cell resolutionDonna L. Farber0Peter A. Sims1Columbia Center for Translational Immunology, Columbia University Irving Medical CenterDepartment of Systems Biology, Columbia University Irving Medical CenterEditorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease.http://link.springer.com/article/10.1186/s13073-019-0645-7
collection DOAJ
language English
format Article
sources DOAJ
author Donna L. Farber
Peter A. Sims
spellingShingle Donna L. Farber
Peter A. Sims
Dissecting lung development and fibrosis at single-cell resolution
Genome Medicine
author_facet Donna L. Farber
Peter A. Sims
author_sort Donna L. Farber
title Dissecting lung development and fibrosis at single-cell resolution
title_short Dissecting lung development and fibrosis at single-cell resolution
title_full Dissecting lung development and fibrosis at single-cell resolution
title_fullStr Dissecting lung development and fibrosis at single-cell resolution
title_full_unstemmed Dissecting lung development and fibrosis at single-cell resolution
title_sort dissecting lung development and fibrosis at single-cell resolution
publisher BMC
series Genome Medicine
issn 1756-994X
publishDate 2019-05-01
description Editorial summary Single-cell transcriptome profiling has enabled high-resolution analysis of cellular populations in tissues during development, health, and disease. Recent studies make innovative use of single-cell RNA sequencing (scRNAseq) to investigate mechanisms that allow immune cells to interact with tissue components in the lung during development and fibrotic lung disease.
url http://link.springer.com/article/10.1186/s13073-019-0645-7
work_keys_str_mv AT donnalfarber dissectinglungdevelopmentandfibrosisatsinglecellresolution
AT peterasims dissectinglungdevelopmentandfibrosisatsinglecellresolution
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