Fallacious Carcinoma-Spindle Cell Variant of Squamous Cell Carcinoma

• Main Authors: Radhika M Bavle, Girish Govinda, Padmalatha Gundappanayakanahalli Venkataramanaiah, Sudhakara Muniswamappa, Reshma Venugopal
• Format: Article
• Language: English
• Published: JCDR Research and Publications Private Limited 2016-07-01
• Series: Journal of Clinical and Diagnostic Research
• Subjects: alveolar ridge-(mandible); biphasic histopathology; carcinosacoma; lane’s tumour
• Online Access: https://jcdr.net/articles/PDF/8099/16400_CE[Ra1]_F(GH)_PF1(SWAK)_PFA(AK)_PF2(PAG).pdf

Spindle cell carcinoma is a unique, rare and peculiar biphasic tumour of head and neck which is not frequently observed in the oral cavity. This variant of squamous cell carcinoma although of monophasic epithelial origin, simulates a sarcoma and is an aggressive carcinoma with high frequency of recurrence and metastasis. A correct and timely diagnosis is of paramount importance. Most of the tumours require an Immunohistochemistry (IHC) panel for confirmation or diagnosis. We report a case of spindle cell carcinoma with varied histopathological morphology and clinical presentation in a middle aged female with a brief review of literature.