Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistance

<p>Abstract</p> <p>Background</p> <p>Thus far gene therapy strategies for HIV/AIDS have used either conventional retroviral vectors or lentiviral vectors for gene transfer. Although highly efficient, their use poses a certain degree of risk in terms of viral mediated on...

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Bibliographic Details
Main Authors: Akkina Ramesh, Tamhane Mayur
Format: Article
Language:English
Published: BMC 2008-07-01
Series:AIDS Research and Therapy
Online Access:http://www.aidsrestherapy.com/content/5/1/16