Comparative data of the revelation of lupous anticoagulant effects with Russell viper and Central Asian gyurza venoms

• Main Authors: Z. S. Barkagan, G. V. Serdyuk, L. P. Tsyvkina, A. P. Momot
• Format: Article
• Language: English
• Published: Siberian State Medical University (Tomsk) 2004-03-01
• Series: Bûlleten' Sibirskoj Mediciny
• Subjects: antiphospholipin syndrome; lupous anticoagulants; diluted central asian gyurza venom; diluted russell viper venom; plasma meager by thrombocytes; antiphospholipin antibodies
• Online Access: https://bulletin.tomsk.ru/jour/article/view/3597

For identification of lupous anticoagulant (LA) effects tests with phospholipin-dependent coagulase of snake venoms are used. Abroad they use the diluted Russell viper venom for this purpose.Investigations carried out by the authors on 31 patients (10 men and 21 women) aged 25-51 with antiphospholipin syndrome registered by clinical and laboratory criterions, have shown that the coagulation test with diluted Central Asian gyurza (Vipera lebetina turanica) venom could be used for the same purpose, its coagulase by the action mechanism is close to the coagulase of Russell viper venom (Vipers Russelli).