Qualitative properties and hopf bifurcation in haematopoietic disease model with chemotherapy

In this paper, we consider a model describing the dynamics of Hematopoietic Stem Cells (HSC) disease with chemotherapy. The model is given by a system of three ordinary differential equations with discrete delay. Its dynamics are studied in term of local stability of the possible steady states for...

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Bibliographic Details
Main Authors: Yafia R., Aziz-Alaoui M. A., Tridane A., Rihan F.
Format: Article
Language:English
Published: EDP Sciences 2014-01-01
Series:MATEC Web of Conferences
Online Access:http://dx.doi.org/10.1051/matecconf/20141610007
Description
Summary:In this paper, we consider a model describing the dynamics of Hematopoietic Stem Cells (HSC) disease with chemotherapy. The model is given by a system of three ordinary differential equations with discrete delay. Its dynamics are studied in term of local stability of the possible steady states for the case without drug intervention term. We prove the existence of periodic oscillations for each case when the delay passes trough a critical values. In the end, we illustrate our results by some numerical simulations.
ISSN:2261-236X