Immune reconstitution of HLA-A*0201/BMLF1- and HLA-A*1101/LMP2-specific Epstein Barr virus cytotoxic T lymphocytes within 90 days after haploidentical hematopoietic stem cell transplantation

Immune reconstitution of HLA-A*0201/BMLF1- and HLA-A*1101/LMP2-specific Epstein Barr virus cytotoxic T lymphocytes within 90 days after haploidentical hematopoietic stem cell transplantation

Abstract Background Haploidentical hematopoietic stem cell transplant (haplo-HSCT) recipients are at high risk for Epstein Barr virus (EBV)-related diseases. EBV-specific CD8+ cytotoxic T cells can control EBV-infected B cell expansion; however, no studies have investigated EBV-specific immune recon...

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Bibliographic Details
Main Authors: Ling Zhou, Dao-pei Lu
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Virology Journal
Subjects:
Haploidentical hematopoietic stem cell transplantation
Epstein-Barr virus
CD8 cells
Pentamers
Online Access:http://link.springer.com/article/10.1186/s12985-019-1123-y

Internet

http://link.springer.com/article/10.1186/s12985-019-1123-y

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