B7h-expressing dendritic cells and plasma B cells mediate distinct outcomes of ICOS costimulation in T cell-dependent antibody responses
<p>Abstract</p> <p>Background</p> <p>The ICOS-B7h costimulatory receptor-ligand pair is required for germinal center formation, the production of isotype-switched antibodies, and antibody affinity maturation in response to T cell-dependent antigens. However, the potenti...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-06-01
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| Series: | BMC Immunology |
| Subjects: | |
| Online Access: | http://www.biomedcentral.com/1471-2172/13/29 |