Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS

Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS

Although the prospects for successful treatment of Mycobacterium avium complex (MAC) infection in AIDS recently seemed quite dismal, the introduction of the semisynthetic macrolides, clarithromycin and azithromycin, has altered this perspective. Several recent clinical studies have been key to our u...

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Main Author: Carol A Kemper
Format: Article
Language:English
Published: Hindawi Limited 1994-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1994/549025
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spelling doaj-05b729a43cfa42b2a71d4188149f90132020-11-24T22:27:32ZengHindawi LimitedCanadian Journal of Infectious Diseases1180-23321994-01-015Suppl B14B20B10.1155/1994/549025Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDSCarol A Kemper0Division of Infectious Diseases, Department of Medicine, Santa Clara Valley Medical Center, San Jose, USAAlthough the prospects for successful treatment of Mycobacterium avium complex (MAC) infection in AIDS recently seemed quite dismal, the introduction of the semisynthetic macrolides, clarithromycin and azithromycin, has altered this perspective. Several recent clinical studies have been key to our understanding of the successful management of these patients and are the basis of this review. Yet, some patients with disseminated MAC remain poorly responsive to therapy, intolerance often limits therapy, and recrudescent bacteremia often occurs. Though our understanding of this infection has been rapidly advanced in the past three years. much remains to be learned about its optimal therapeutic management.http://dx.doi.org/10.1155/1994/549025
collection DOAJ
language English
format Article
sources DOAJ
author Carol A Kemper
spellingShingle Carol A Kemper
Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS
Canadian Journal of Infectious Diseases
author_facet Carol A Kemper
author_sort Carol A Kemper
title Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS
title_short Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS
title_full Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS
title_fullStr Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS
title_full_unstemmed Advances in the Treatment of Desseminated Mycobacterium avium Complex in Adults with AIDS
title_sort advances in the treatment of desseminated mycobacterium avium complex in adults with aids
publisher Hindawi Limited
series Canadian Journal of Infectious Diseases
issn 1180-2332
publishDate 1994-01-01
description Although the prospects for successful treatment of Mycobacterium avium complex (MAC) infection in AIDS recently seemed quite dismal, the introduction of the semisynthetic macrolides, clarithromycin and azithromycin, has altered this perspective. Several recent clinical studies have been key to our understanding of the successful management of these patients and are the basis of this review. Yet, some patients with disseminated MAC remain poorly responsive to therapy, intolerance often limits therapy, and recrudescent bacteremia often occurs. Though our understanding of this infection has been rapidly advanced in the past three years. much remains to be learned about its optimal therapeutic management.
url http://dx.doi.org/10.1155/1994/549025
work_keys_str_mv AT carolakemper advancesinthetreatmentofdesseminatedmycobacteriumaviumcomplexinadultswithaids
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