A systematic analysis of the application of diagnostic criteria for drug-induced liver injury in China based on the literature

ObjectiveTo investigate the application of diagnostic criteria for drug-induced liver injury in China. MethodsCNKI, VIP, and Wanfang Data were searched for articles published from 1990 to 2015, and the diagnostic criteria in the articles were recorded to investigate the current application of diagno...

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Bibliographic Details
Main Authors: ZHANG Dong, ZHANG Tao, WU Yunan
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2017-05-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=8202
Description
Summary:ObjectiveTo investigate the application of diagnostic criteria for drug-induced liver injury in China. MethodsCNKI, VIP, and Wanfang Data were searched for articles published from 1990 to 2015, and the diagnostic criteria in the articles were recorded to investigate the current application of diagnostic criteria for drug-induced liver injury. ResultsA total of 609 articles were included, with 410 articles of case studies and 199 case reports. A total of 15 types of diagnostic criteria were used in China, and only 13.4% of these articles used the causality assessment method recommended by the international community. In 46% of the cases reported in the articles, a diagnosis was made based on clinical symptoms and exclusion of common causes of liver injury. ConclusionThere are many diagnostic criteria for drug-induced liver injury in China, and the diagnosis is subjective and lacks rigor.
ISSN:1001-5256
1001-5256