Light-inducible antimiR-92a as a therapeutic strategy to promote skin repair in healing-impaired diabetic mice
Inhibition of microRNAs using antimiRs is a potential therapeutic option for a number of diseases, but systemic inhibition may cause adverse effects. Here the authors develop light-activated antimiRs directed against miR-92a, and show localized inhibition in the skin and improved wound healing in di...
Main Authors: | Tina Lucas, Florian Schäfer, Patricia Müller, Sabine A. Eming, Alexander Heckel, Stefanie Dimmeler |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms15162 |
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