Cicatricial pemphygoid in the upper aerodigestive tract: report of two cases

• Main Authors: Vinicius Antunes Freitas, Helena Maria Gonçalves Becker, Roberto Eustáquio Santos Guimarães, Letícia Paiva Franco, Fernando Fernandes Guimarães, Marcelo Figueredo Martins, Paulo Fernando Tormin Crosara
• Format: Article
• Language: English
• Published: Elsevier 2008-11-01
• Series: Brazilian Journal of Otorhinolaryngology
• Online Access: http://www.sciencedirect.com/science/article/pii/S1808869415301580

Summary: Cicatricial pemphygoid (mucous membrane cicatricial pemphygoid) is a chronic autoimmune inflammatory disease characterized by subepithelial bubbles in mucous membranes and, occasionally on the skin. It may affect the mouth, the nose, pharynx, larynx, the eyes, esophagus, anus, genitals and skin; especially affecting patients between fifty and sixty years of life. Treatment includes systemic steroids and immunosuppressive agents. In the present paper we describe two cases with the active disease, and one of them had sepsis because of using immunosuppressive agents and another that presented supraglottic stenosis requiring tracheostomy. Keywords: scars, pemphygoid, aerodigestive tract