Cicatricial pemphygoid in the upper aerodigestive tract: report of two cases

Summary: Cicatricial pemphygoid (mucous membrane cicatricial pemphygoid) is a chronic autoimmune inflammatory disease characterized by subepithelial bubbles in mucous membranes and, occasionally on the skin. It may affect the mouth, the nose, pharynx, larynx, the eyes, esophagus, anus, genitals and...

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Main Authors: Vinicius Antunes Freitas, Helena Maria Gonçalves Becker, Roberto Eustáquio Santos Guimarães, Letícia Paiva Franco, Fernando Fernandes Guimarães, Marcelo Figueredo Martins, Paulo Fernando Tormin Crosara
Format: Article
Language:English
Published: Elsevier 2008-11-01
Series:Brazilian Journal of Otorhinolaryngology
Online Access:http://www.sciencedirect.com/science/article/pii/S1808869415301580
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Summary:Summary: Cicatricial pemphygoid (mucous membrane cicatricial pemphygoid) is a chronic autoimmune inflammatory disease characterized by subepithelial bubbles in mucous membranes and, occasionally on the skin. It may affect the mouth, the nose, pharynx, larynx, the eyes, esophagus, anus, genitals and skin; especially affecting patients between fifty and sixty years of life. Treatment includes systemic steroids and immunosuppressive agents. In the present paper we describe two cases with the active disease, and one of them had sepsis because of using immunosuppressive agents and another that presented supraglottic stenosis requiring tracheostomy. Keywords: scars, pemphygoid, aerodigestive tract
ISSN:1808-8694