RBM39 Alters Phosphorylation of c-Jun and Binds to Viral RNA to Promote PRRSV Proliferation

RBM39 Alters Phosphorylation of c-Jun and Binds to Viral RNA to Promote PRRSV Proliferation

As transcriptional co-activator of AP-1/Jun, estrogen receptors and NF-κB, nuclear protein RBM39 also involves precursor mRNA (pre-mRNA) splicing. Porcine reproductive and respiratory syndrome virus (PRRSV) causes sow reproductive disorders and piglet respiratory diseases, which resulted in serious...

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Bibliographic Details
Main Authors: Yinna Song, Yanyu Guo, Xiaoyang Li, Ruiqi Sun, Min Zhu, Jingxuan Shi, Zheng Tan, Lilin Zhang, Jinhai Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
RBM39
c-Jun
porcine reproductive and respiratory syndrome virus
AP-1
phosphorylation
interferon
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.664417/full

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