Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid.

Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid.

<h4>Background</h4>Cannabidiol (CBD) confers therapeutic effects in some neurological disorders via modulation of inflammatory, oxidative and cell-signalling pathways. However, CBD is lipophilic and highly photooxidative with low oral bioavailability in plasma and brain. In this study, w...

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Bibliographic Details
Main Authors: Maimuna Majimbi, Emily Brook, Peter Galettis, Edward Eden, Hani Al-Salami, Armin Mooranian, Hesham Al-Sallami, Virginie Lam, John C L Mamo, Ryusuke Takechi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0243858

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