The Role of Inflammatory Proteins in Anti-Glucocorticoid Therapy for Treatment-Resistant Depression

The Role of Inflammatory Proteins in Anti-Glucocorticoid Therapy for Treatment-Resistant Depression

Background: Optimising treatments for patients with treatment-resistant depression (TRD) is key to reducing the burden of this severe illness. The anti-glucocorticoid medication metyrapone has mixed evidence supporting a role as a possible augmentation treatment in TRD. The degree of treatment resis...

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Bibliographic Details
Main Authors: Rebecca Strawbridge, Alzbeta Jamieson, John Hodsoll, Ian Nicol Ferrier, Richard Hamish McAllister-Williams, Timothy R. Powell, Allan H. Young, Anthony J. Cleare, Stuart Watson
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
depression
inflammation
metyrapone
glucocorticoid
augmentation
treatment-resistance
Online Access:https://www.mdpi.com/2077-0383/10/4/784

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