Quality of life and adherence to treatment of patients with chronic viral hepatitis C

• Main Authors: R. S. Mirkhaydarov, R. N. Kildibekova, E. R. Iskhakov, P. O. Kazakova
• Format: Article
• Language: Russian
• Published: Scientific Сentre for Family Health and Human Reproduction Problems 2018-04-01
• Series: Acta Biomedica Scientifica
• Subjects: viral hepatitis; quality of life; adherence to treatment
• Online Access: https://www.actabiomedica.ru/jour/article/view/557
• ISSN: 2541-9420; 2587-9596

Background. The problem of viral hepatitis C in the modern world is rather acute for public health service. The patients themselves, their striving for recovery, desire to have the quality of live on the same level as a healthy person has and the understanding of the necessity to obey the a doctor's recommendations play the significant role in the successful treatment of this disease. The aim of the given work is the study of the quality of life and the adherence to treatment of young people with chronic viral hepatitis C and the following analysis of the results. Materials and methods. In the process of research, 138 men at the age of 18-45 with chronic viral hepatitis were examined. The verification of the diagnosis occurred on the basis of international classification of chronic hepatitis (Los Angeles, 1994), and also 1CD10 (B17.1), besides, the HCVRNA for more than 6 months was also taken into account. Twenty-five apparently healthy men 18-45 years old were included in this group. The quality of life was clarified with the help of short form of the adapted Russified specialized questionnaire "Medical Outcomes Study, Short Form" (SF36 Health Study Survey). Statistical data processing was carried out with the use of application package "Statistica for Windows", version 7.0. Results. The minimum index in the group of the patients with chronical viral hepatitis C was the index of social activity (SF) - 46.2 ± 0.8 points. In this group, the index of physical pain (BP) was at its maximum. The study of the adherence to treatment depending on the quality of life stays acute. Conclusions. During the course of this work, the peculiarities of the quality of life scales were determined according to the SF-36 Health Study Survey among the patients with chronic viral hepatitis C and the correlations with the adherence to treatment.