Evaluating rare amino acid substitutions (RGC_CAMs) in a yeast model clade.

When inferring phylogenetic relationships, not all sites in a sequence alignment are equally informative. One recently proposed approach that takes advantage of this inequality relies on sites that contain amino acids whose replacement requires multiple substitutions. Identifying these so-called RGC...

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Bibliographic Details
Main Authors: Kenneth Polzin, Antonis Rokas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3956930?pdf=render