Methanolic leaf extract of Punica granatum attenuates ischemia-reperfusion brain injury in Wistar rats: Potential antioxidant and anti-inflammatory mechanisms

Methanolic leaf extract of Punica granatum attenuates ischemia-reperfusion brain injury in Wistar rats: Potential antioxidant and anti-inflammatory mechanisms

Objective(s): This study was conducted to evaluate the cerebroprotective effect of methanolic leaf extract of Punica granatum (MePG) in Wistar rats.Materials and Methods: The MePG was initially assessed for in vitro antioxidant activity, and later evaluated on LPS-induced RAW 264.7 cell line assay....

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Bibliographic Details
Main Authors: Gollapalle Lakshminarayanashastry Viswanatha, Marikunte Venkatanarasappa Venkataranganna, Nunna Bheema Lingeswara Prasad
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2019-02-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Antioxidant
Cerebral ischemia
Neuroprotection
Punica granatum
Stroke
Online Access:http://ijbms.mums.ac.ir/article_12012_277637073b0faa2750192e26d2bb8c03.pdf

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