Fast and SNP-aware short read alignment with SALT

Abstract Background DNA sequence alignment is a common first step in most applications of high-throughput sequencing technologies. The accuracy of sequence alignments directly affects the accuracy of downstream analyses, such as variant calling and quantitative analysis of transcriptome; therefore,...

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Bibliographic Details
Main Authors: Wei Quan, Bo Liu, Yadong Wang
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BMC Bioinformatics
Subjects:
NGS
Online Access:https://doi.org/10.1186/s12859-021-04088-6