Fast and SNP-aware short read alignment with SALT
Abstract Background DNA sequence alignment is a common first step in most applications of high-throughput sequencing technologies. The accuracy of sequence alignments directly affects the accuracy of downstream analyses, such as variant calling and quantitative analysis of transcriptome; therefore,...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-08-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-021-04088-6 |