A complex between the Zika virion and the Fab of a broadly cross-reactive neutralizing monoclonal antibody revealed by cryo-EM and single particle analysis at 4.1 Å resolution
Zika virus (ZIKV) recently emerged as a major public health concern because it can cause fetal microcephaly and neurological disease such as the Guillain-Barré syndrome. A particularly potent class of broadly neutralizing antibodies (nAbs) targets a quaternary epitope located at the interface of two...
Main Authors: | Anu Tyagi, Tofayel Ahmed, Jian Shi, Shashi Bhushan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Journal of Structural Biology: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590152420300106 |
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