CircFAM73A promotes the cancer stem cell-like properties of gastric cancer through the miR-490-3p/HMGA2 positive feedback loop and HNRNPK-mediated β-catenin stabilization

CircFAM73A promotes the cancer stem cell-like properties of gastric cancer through the miR-490-3p/HMGA2 positive feedback loop and HNRNPK-mediated β-catenin stabilization

Abstract Background Circular RNAs (circRNAs) have emerged as a new subclass of regulatory RNAs that play critical roles in various cancers. Cancer stem cells (CSCs), a small subset of cancer cells, are believed to possess the capacities to initiate tumorigenesis and promote progression. Although acc...

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Bibliographic Details
Main Authors: Yiwen Xia, Jialun Lv, Tianlu Jiang, Bowen Li, Ying Li, Zhongyuan He, Zhe Xuan, Guangli Sun, Sen Wang, Zheng Li, Weizhi Wang, Linjun Wang, Zekuan Xu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:https://doi.org/10.1186/s13046-021-01896-9

Internet

https://doi.org/10.1186/s13046-021-01896-9

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