Evaluation of Morpholino Antisense Oligos’ Role on BCR-ABL Gene Silencing in the K562 Cell Line

Evaluation of Morpholino Antisense Oligos’ Role on BCR-ABL Gene Silencing in the K562 Cell Line

Objective: Chronic myeloid leukemia (CML) develops when a hematopoietic stem cellacquires the BCR/ABL fusion gene. This causes these transformed hematopoietic cellsto have a greater than normal proliferation rate. Scientists attempt to improve the CMLtreatment process by silencing the BCR/ABL oncoge...

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Bibliographic Details
Main Authors: Bahman Delalat, Soraya Rasi Ghaemi, Saeid Abroun, Mehrdad Noruzinia, Mahmoud Haririan, Masoud Soleimani, Saeid Kaviani
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2010-01-01
Series:Cell Journal
Subjects:
Chronic Myeloid Leukemia
Morpholino Antisense
K562
BCR/ABL Gene
Online Access:http://celljournal.org/library/upload/article/af_4629369Haririan.pdf

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