Deglycosylated Azithromycin Targets Transgelin to Enhance Intestinal Smooth Muscle Function
Summary: Azithromycin (AZM) has been widely used as an antibacterial drug for many years. It has also been used to treat delayed gastric emptying. However, it exerts several side effects. We found that deglycosylated AZM (Deg-AZM or CP0119), an AZM metabolite, is a positively strong intestinal agoni...
Main Authors: | Weilong Zhong, Bo Sun, Hao Ruan, Guang Yang, Baoxin Qian, Hailong Cao, Lingfei He, Yunjing Fan, Arthur G. Roberts, Xiang Liu, Xuejiao Hu, Yuan Liang, Qing Ye, Tingting Yin, Bangmao Wang, Cheng Yang, Tao Sun, Honggang Zhou |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-09-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220306568 |
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