The influence of vitamin E supplementation on the oxidative status of rat liver

• Main Authors: Đurašević S.F., Đorđević Jelena, Jasnić N., Lakić Iva, Vujović P., Cvijić Gordana
• Format: Article
• Language: English
• Published: University of Belgrade, University of Novi Sad 2010-01-01
• Series: Archives of Biological Sciences
• Subjects: vitamin E; α-tocopheryl-succinate; liver; antioxidative protection; rats
• Online Access: http://www.doiserbia.nb.rs/img/doi/0354-4664/2010/0354-46641003677D.pdf

We tested to see if the additional intake of vitamin E in the form of α-tocopheryl-succinate would improve liver antioxidative protection. Thus, we studied the tissue oxidative status in rats supplemented by two doses of the antioxidant over a four week period of time. Our results confirmed that the additional intake of vitamin E decreased the liver lipid peroxidation level and SOD activity level and preserved its vitamin C content. However, the hydrogen peroxide content and catalase activity remained unchanged, probably due to the mechanism of vitamin E liver metabolism. .