Predicting different pathological grades with contrast-enhanced MR imaging in oligodendrogliomas

Medical image processing and its quantitative analysis plays a vital role in several clinical scenarios, such as diagnosis as well as treatment. The results of this study show that there are 478 mRNAs differentially expressed in low grade as compared to anaplastic oligodendroglial tumor (2 Fold grea...

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Bibliographic Details
Main Authors: Jun Zhao, Tiejun Gan, Jianhong Zhao, Junjie Mao, Wenjuan Zhang, Xiaoying Guan, Junlin Zhou
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Alexandria Engineering Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S1110016820305688
Description
Summary:Medical image processing and its quantitative analysis plays a vital role in several clinical scenarios, such as diagnosis as well as treatment. The results of this study show that there are 478 mRNAs differentially expressed in low grade as compared to anaplastic oligodendroglial tumor (2 Fold greater, p < 0.05) group. These genes participated in Gene Ontology and KEGG pathways such as cell migration, cell motility, and cytokine-cytokine receptor interaction. Oligodendroglial classification models derived from advanced imaging will improve the accuracy of tumor grading, provide prognostic information, and have potential to influence treatment decisions.
ISSN:1110-0168