Prednisolone Alters Endometrial Decidual Cells and Affects Decidual-Trophoblast Interactions

Prednisolone Alters Endometrial Decidual Cells and Affects Decidual-Trophoblast Interactions

Poor pregnancy outcomes such as recurrent pregnancy loss (RPL) and preeclampsia are associated with impaired decidualization and abnormal trophoblast invasion. Emerging evidence suggests that use of corticosteroids, including prednisolone affects fertility by altering uterine function and may be ass...

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Bibliographic Details
Main Authors: Eliza Grbac, Teresa So, Swati Varshney, Nicholas Williamson, Evdokia Dimitriadis, Ellen Menkhorst
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
prednisolone
decidualization
trophoblast
recurrent pregnancy loss
preeclampsia
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.647496/full

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