Apolipoprotein E4 (1–272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells

<p>Abstract</p> <p>Background</p> <p>Apolipoprotein E allele ε4 (apoE4) is a strong risk factor for developing Alzheimer's disease (AD). Secreted apoE has a critical function in redistributing lipids among central nervous system cells to maintain normal lipid homeo...

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Bibliographic Details
Main Authors: Michikawa Makoto, Hosono Takashi, Fujino Takahiro, Watanabe Atsushi, Nakamura Toshiyuki
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/4/1/35