An Efficient and Easy-to-Use Network-Based Integrative Method of Multi-Omics Data for Cancer Genes Discovery

An Efficient and Easy-to-Use Network-Based Integrative Method of Multi-Omics Data for Cancer Genes Discovery

Identifying personalized driver genes is essential for discovering critical biomarkers and developing effective personalized therapies of cancers. However, few methods consider weights for different types of mutations and efficiently distinguish driver genes over a larger number of passenger genes....

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Bibliographic Details
Main Authors: Ting Wei, Botao Fa, Chengwen Luo, Luke Johnston, Yue Zhang, Zhangsheng Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Genetics
Subjects:
multi-omics
network-based methods
cancer gene prediction
driver genes
tumor stratification
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.613033/full

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