Intracellular and Intercellular Signalling Mechanisms following DNA Damage Are Modulated By PINK1

Intracellular and Intercellular Signalling Mechanisms following DNA Damage Are Modulated By PINK1

Impaired mitochondrial function and accumulation of DNA damage have been recognized as hallmarks of age-related diseases. Mitochondrial dysfunction initiates protective signalling mechanisms coordinated at nuclear level particularly by modulating transcription of stress signalling factors. In turn,...

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Bibliographic Details
Main Authors: Mihaela Temelie, Diana Iulia Savu, Nicoleta Moisoi
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/1391387

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