Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination

Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination

Mohammad A RashadOphthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, EgyptPurpose: To evaluate the success rate of a modified bleb needling technique in eyes with previous glaucoma surgery that had elevated intraocular pressure.Methods: A retrospective study of 24 eyes of 24...

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Main Author: Rashad MA
Format: Article
Language:English
Published: Dove Medical Press 2012-12-01
Series:Clinical Ophthalmology
Online Access:http://www.dovepress.com/efficacy-of-repeated-5-fluorouracil-needling-for-failing-and-failed-fi-a11830
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spelling doaj-0507734865f946b1a6915490ec0eca482020-11-24T23:30:35ZengDove Medical PressClinical Ophthalmology1177-54671177-54832012-12-012013default1522Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examinationRashad MAMohammad A RashadOphthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, EgyptPurpose: To evaluate the success rate of a modified bleb needling technique in eyes with previous glaucoma surgery that had elevated intraocular pressure.Methods: A retrospective study of 24 eyes of 24 patients that underwent repeated bleb needling performed for failing and failed blebs on slit lamp with 5-fluorouracil (5-FU) injections on demand. This was performed after gonioscopic examination to define levels of filtration block.Results: There was significant reduction of mean IOP from 36.91 mmHg to 14.73 mmHg at the final follow-up (P < 0.001). The overall success rate was 92%.Conclusion: Repeated needling with adjunctive 5-FU proved a highly effective, safe alternative to revive filtration surgery rather than another medication or surgery.Keywords: bleb, failure, 5-FU, needling, gonioscopyhttp://www.dovepress.com/efficacy-of-repeated-5-fluorouracil-needling-for-failing-and-failed-fi-a11830
collection DOAJ
language English
format Article
sources DOAJ
author Rashad MA
spellingShingle Rashad MA
Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination
Clinical Ophthalmology
author_facet Rashad MA
author_sort Rashad MA
title Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination
title_short Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination
title_full Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination
title_fullStr Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination
title_full_unstemmed Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination
title_sort efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination
publisher Dove Medical Press
series Clinical Ophthalmology
issn 1177-5467
1177-5483
publishDate 2012-12-01
description Mohammad A RashadOphthalmology Department, Faculty of Medicine, Ain Shams University, Cairo, EgyptPurpose: To evaluate the success rate of a modified bleb needling technique in eyes with previous glaucoma surgery that had elevated intraocular pressure.Methods: A retrospective study of 24 eyes of 24 patients that underwent repeated bleb needling performed for failing and failed blebs on slit lamp with 5-fluorouracil (5-FU) injections on demand. This was performed after gonioscopic examination to define levels of filtration block.Results: There was significant reduction of mean IOP from 36.91 mmHg to 14.73 mmHg at the final follow-up (P < 0.001). The overall success rate was 92%.Conclusion: Repeated needling with adjunctive 5-FU proved a highly effective, safe alternative to revive filtration surgery rather than another medication or surgery.Keywords: bleb, failure, 5-FU, needling, gonioscopy
url http://www.dovepress.com/efficacy-of-repeated-5-fluorouracil-needling-for-failing-and-failed-fi-a11830
work_keys_str_mv AT rashadma efficacyofrepeated5fluorouracilneedlingforfailingandfailedfilteringsurgeriesbasedonsimplegonioscopicexamination
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