The Function of Sialidase Revealed by Sialidase Activity Imaging Probe

The Function of Sialidase Revealed by Sialidase Activity Imaging Probe

Sialidase cleaves sialic acid residues from glycans such as glycoproteins and glycolipids. In the brain, desorption of the sialic acid by sialidase is essential for synaptic plasticity, learning and memory and synaptic transmission. BTP3-Neu5Ac has been developed for sensitive imaging of sialidase e...

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Bibliographic Details
Main Authors: Akira Minami, Yuuki Kurebayashi, Tadanobu Takahashi, Tadamune Otsubo, Kiyoshi Ikeda, Takashi Suzuki
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
sialidase
BTP3-Neu5Ac
BTP9-Neu5Ac
hippocampus
memory
glutamate
Online Access:https://www.mdpi.com/1422-0067/22/6/3187

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