Spatial and temporal boundaries of NMDA receptor hypofunction leading to schizophrenia
Abstract The N-methyl-d-aspartate receptor hypofunction is one of the most prevalent models of schizophrenia. For example, healthy subjects treated with uncompetitive N-methyl-d-aspartate receptor antagonists elicit positive, negative, and cognitive-like symptoms of schizophrenia. Patients with anti...
Main Authors: | Kazu Nakazawa, Vivek Jeevakumar, Kazuhito Nakao |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-02-01
|
Series: | npj Schizophrenia |
Online Access: | https://doi.org/10.1038/s41537-016-0003-3 |
Similar Items
-
Contribution of NMDA receptor hypofunction in prefrontal and cortical excitatory neurons to schizophrenia-like phenotypes.
by: Gregory R Rompala, et al.
Published: (2013-01-01) -
5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction
by: Fitzgerald, A., et al.
Published: (2022) -
NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia
by: Wen-Jun eGao, et al.
Published: (2013-03-01) -
Altered excitatory-inhibitory balance in the NMDA-hypofunction model of schizophrenia
by: Colin Kehrer, et al.
Published: (2008-04-01) -
The cannabinoid receptor 1 associates with NMDA receptors to produce glutamatergic hypofunction: implications in psychosis and schizophrenia.
by: Pilar eSánchez-Blázquez, et al.
Published: (2014-01-01)