A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice

A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice

We developed a bacterial expression system to produce a recombinant disintegrin, vicrostatin (VCN), whose structure is based on a natural disintegrin isolated from southern copperhead snake venom. Our goal is to develop VCN for potential clinical translation as an anti-cancer agent. VCN is a peptide...

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Bibliographic Details
Main Authors:	Steve Swenson, Radu O. Minea, Cao Duc Tuan, Thu-Zan Thein, Thomas C. Chen, Francis S. Markland
Format:	Article
Language:	English
Published:	MDPI AG 2018-11-01
Series:	Molecules
Subjects:	disintegrin glioblastoma integrin brachytherapy radioiodine vicrostatin cancer therapy
Online Access:	https://www.mdpi.com/1420-3049/23/11/2918

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