Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial.

Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial.

BACKGROUND: Blockade of the renin-angiotensin system (RAS) reduces the incidence of type 2 diabetes mellitus. In rodents, it has been demonstrated that RAS blockade improved adipose tissue (AT) function and glucose homeostasis. However, the effects of long-term RAS blockade on AT function have not b...

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Main Authors: Gijs H Goossens, Chantalle C M Moors, Nynke J van der Zijl, Nicolas Venteclef, Rohia Alili, Johan W E Jocken, Yvonne Essers, Jack P Cleutjens, Karine Clément, Michaela Diamant, Ellen E Blaak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3386933?pdf=render

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