The Genetic Architecture of Type 1 Diabetes

Type 1 diabetes (T1D) is classically characterised by the clinical need for insulin, the presence of disease-associated serum autoantibodies, and an onset in childhood. The disease, as with other autoimmune diseases, is due to the interaction of genetic and non-genetic effects, which induce a destru...

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Bibliographic Details
Main Authors: Samuel T Jerram, Richard David Leslie
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/8/8/209