Comparative metabolic profiling of engineered Saccharomyces cerevisiae with enhanced flavonoids production

Comparative metabolic profiling of engineered Saccharomyces cerevisiae with enhanced flavonoids production

The engineered Saccharomyces cerevisiae strains with ARO4K229L-overexpression, PHA2-downregulation and ARO10/PDC5-knockouts, were previously shown to have enhanced accumulation of naringenin. To understand the mechanism behind this, comparative metabolomic analysis was performed, to gain a global ov...

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Bibliographic Details
Main Authors: Xiaomei Lyu, Kuan Rei Ng, Rita Mark, Jie Lin Lee, Wei Ning Chen
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Journal of Functional Foods
Subjects:
Metabolomic analysis
Flavonoids
S. cerevisiae
Regulation mechanism
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618300987

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