Causes and consequences of hyperexcitation in central clock neurons.

Hyperexcited states, including depolarization block and depolarized low amplitude membrane oscillations (DLAMOs), have been observed in neurons of the suprachiasmatic nuclei (SCN), the site of the central mammalian circadian (~24-hour) clock. The causes and consequences of this hyperexcitation have...

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Bibliographic Details
Main Authors: Casey O Diekman, Mino D C Belle, Robert P Irwin, Charles N Allen, Hugh D Piggins, Daniel B Forger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3749949?pdf=render