Characterization of endothelial cell injury by cholesterol oxidation products found in oxidized LDL.

Characterization of endothelial cell injury by cholesterol oxidation products found in oxidized LDL.

The present study describes the toxicity of oxidized LDL towards rabbit aortic endothelial cells in terms of its lipid components with specific attention to the cholesterol oxidation products (ChOx) found in oxidized LDL isolated from human plasma. Measurements of the major ChOx associated with fres...

Full description

Bibliographic Details
Main Authors:	A Sevanian, H N Hodis, J Hwang, L L McLeod, H Peterson
Format:	Article
Language:	English
Published:	Elsevier 1995-09-01
Series:	Journal of Lipid Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S0022227520411150

Similar Items

Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-).
by: H.N. Hodis, et al.
Published: (1994-04-01)

Uptake, metabolism, and cytotoxicity of isomeric cholesterol-5,6-epoxides in rabbit aortic endothelial cells.
by: A Sevanian, et al.
Published: (1991-01-01)

Impact of LDL carotenoid and α-tocopherol content on LDL oxidation by endothelial cells in culture
by: Tammy R. Dugas, et al.
Published: (1998-05-01)

LDL- is a lipid hydroperoxide-enriched circulating lipoprotein
by: A Sevanian, et al.
Published: (1997-03-01)

Effects of oxidatively modified LDL on cholesterol esterification in cultured macrophages.
by: HF Zhang, et al.
Published: (1990-08-01)

Nitric oxide, cholesterol oxides and endothelium-dependent vasodilation in plasma of patients with essential hypertension
by: P. Moriel, et al.
Published: (2002-11-01)

Effects of Oxidized LDL on Vascular Endothelial Cell Physiology
by: Chow Shu Er, et al.
Published: (1999)

LDL oxidation by activated monocytes: characterization of the oxidized LDL and requirement for transition metal ions
by: Xiaoyan Xing, et al.
Published: (1998-11-01)

Minimally oxidized LDL is a potent inhibitor of lecithin:cholesterol acyltransferase activity
by: J K Bielicki, et al.
Published: (1996-05-01)

Protective Effects of Berberine against Low-Density Lipoprotein (LDL) Oxidation and Oxidized LDL-Induced Cytotoxicity on Endothelial Cells
by: Shiu-Mei, et al.
Published: (2008)

Protective Effects of Capsaicin against Low-Density Lipoprotein (LDL) Oxidation and Oxidized LDL-Induced Cytotoxicity on Endothelial Cells
by: Yi-Hsun,, et al.
Published: (2012)

Variable Effects Of LDL Subclasses Of Cholesterol On Endothelial Nitric Oxide/Peroxynitrite Balance – The Risks And Clinical Implications For Cardiovascular Disease
by: Hua J, et al.
Published: (2019-11-01)

6-Shogaol Protects against Oxidized LDL-Induced Endothelial Injruries by Inhibiting Oxidized LDL-Evoked LOX-1 Signaling
by: Yun kai Wang, et al.
Published: (2013-01-01)

LDL-Cholesterol Increases the Transcytosis of Molecules through Endothelial Monolayers.
by: Ana Magalhaes, et al.
Published: (2016-01-01)

Caffeic acid, a phenol found in white wine, modulates endothelial nitric oxide production and protects from oxidative stress-associated endothelial cell injury.
by: Massimiliano Migliori, et al.
Published: (2015-01-01)

Effects of LDL cholesterol on vascular function
by: McPherson, Katrine L.
Published: (1996)

Inhibitory Effects of Psidium guajava extract onLow-Density Lipoprotein (LDL) Oxidation and Oxidized LDL-Induced Cytotoxicity in Endothelial Cells
by: Hsiao-Ping Kuo, et al.
Published: (2011)

Protective Effects of Euphorbia lathyris extract against Low-Density Lipoprotein (LDL) Oxidation and Oxidized LDL-Induced Cytotoxicity on Endothelial Cells
by: Jiun-Siang Lin, et al.
Published: (2010)

Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathwayss⃞
by: Ming-Dong Wang, et al.
Published: (2007-03-01)

Differential trafficking of oxidized LDL and oxidized LDL immune complexes in macrophages: impact on oxidative stress.
by: Mohammed M Al Gadban, et al.
Published: (2010-09-01)

Modifications to LDL and endothelial cells by oxidation and n-3 fatty acids
by: Douet, Lisa Jane
Published: (2007)

Protective effects of polyphenolic compounds on oxidized LDL-induced endothelial dysfunction
by: Hsiu-Chung, et al.
Published: (2006)

Acyl-coenzyme A:cholesterol acyltransferase promotes oxidized LDL/oxysterol-induced apoptosis in macrophages
by: Natalie E. Freeman, et al.
Published: (2005-09-01)

Dual role of endothelial nitric oxide synthase in oxidized LDL-induced, p66Shc-mediated oxidative stress in cultured human endothelial cells.
by: Yi Shi, et al.
Published: (2014-01-01)

OxLDL induces macrophage γ-GCS-HS protein expression: a role for oxLDL-associated lipid hydroperoxide in GSH synthesis
by: Lijiang Shen, et al.
Published: (2001-05-01)

Effect of cholesterol and cholesterol analogues on platelet function
by: McLeod, Andrew J.
Published: (1981)

Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria Autophagy
by: Jia Zheng, et al.
Published: (2020-11-01)

Oxidized LDL activates phospholipase A2 to supply fatty acids required for cholesterol esterification
by: Satoshi Akiba, et al.
Published: (2003-09-01)

Is the Ratio of Antibodies Against Oxidized LDL to Oxidized LDL an Indicator of Cardiovascular Risk in Psoriasis?
by: Medha Rajappa, et al.
Published: (2016-09-01)

Effect of probucol on LDL oxidation and atherosclerosis in LDL receptor-deficient mice
by: David A. Bird, et al.
Published: (1998-05-01)

Traffic air pollution and oxidized LDL.
by: Lotte Jacobs, et al.
Published: (2011-01-01)

Protective effects of Co-enzyme Q10 on oxidized LDL-induced endothelial dysfunction
by: Kun-Ling Tsai, et al.
Published: (2013)

Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence
by: Yue-Hua Jiang, et al.
Published: (2020-04-01)

Physiological catalysts of LDL oxidation
by: O'Hagan, C. E.
Published: (2003)

Targeting LDL Cholesterol With LNA
by: Arthur M Krieg
Published: (2012-01-01)

LDL particle size and LDL and HDL cholesterol changes with dietary fat and cholesterol in healthy subjects
by: Peter M. Clifton, et al.
Published: (1998-09-01)

Side-chain oxidation of lipoprotein-bound [24,25-3H]cholesterol in the rat: comparison of HDL and LDL and implications for bile acid synthesis.
by: L K Miller, et al.
Published: (1982-02-01)

DNA scission and LDL cholesterol oxidation inhibition and antioxidant activities of Bael (Aegle marmelos) flower extracts
by: Anoma Chandrasekara, et al.
Published: (2018-07-01)

Elevated Levels of Plasma IgA Autoantibodies against Oxidized LDL Found in Proliferative Diabetic Retinopathy but Not in Nonproliferative Retinopathy
by: Satu Vavuli, et al.
Published: (2016-01-01)

High affinity binding of oxidized LDL to mouse lectin-like oxidized LDL receptor (LOX-1)
by: Hoshikawa, Hajime
Published: (2014)