A Silicon-based Coral-like Nanostructured Microfluidics to Isolate Rare Cells in Human Circulation: Validation by SK-BR-3 Cancer Cell Line and Its Utility in Circulating Fetal Nucleated Red Blood Cells

A Silicon-based Coral-like Nanostructured Microfluidics to Isolate Rare Cells in Human Circulation: Validation by SK-BR-3 Cancer Cell Line and Its Utility in Circulating Fetal Nucleated Red Blood Cells

Circulating fetal cells (CFCs) in maternal blood are rare but have a strong potential to be the target for noninvasive prenatal diagnosis (NIPD). &#8220;Cell Reveal<sup>TM</sup> system&#8222; is a silicon-based microfluidic platform capable to capture rare cell populations in hum...

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Bibliographic Details
Main Authors: Gwo-Chin Ma, Wen-Hsiang Lin, Chung-Er Huang, Ting-Yu Chang, Jia-Yun Liu, Ya-Jun Yang, Mei-Hui Lee, Wan-Ju Wu, Yun-Shiang Chang, Ming Chen
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Micromachines
Subjects:
cbNIPD
fnRBC
capture efficiency
microfluidics
nanostructure
Online Access:https://www.mdpi.com/2072-666X/10/2/132

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