Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway.

Chemoresistance in prostate cancer cells is regulated by miRNAs and Hedgehog pathway.

Many prostate cancers relapse due to the generation of chemoresistance rendering first-line treatment drugs like paclitaxel (PTX) ineffective. The present study aims to determine the role of miRNAs and Hedgehog (Hh) pathway in chemoresistant prostate cancer and to evaluate the combination therapy us...

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Bibliographic Details
Main Authors: Saurabh Singh, Deepak Chitkara, Reza Mehrazin, Stephen W Behrman, Robert W Wake, Ram I Mahato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3386918?pdf=render

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