Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens.

Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens.

BACKGROUND: The persistent evolution of highly pathogenic avian influenza (HPAI) highlights the need for novel vaccination techniques that can quickly and effectively respond to emerging viral threats. We evaluated the use of optimized consensus influenza antigens to provide broad protection against...

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Bibliographic Details
Main Authors: Dominick J Laddy, Jian Yan, Michele Kutzler, Darwyn Kobasa, Gary P Kobinger, Amir S Khan, Jack Greenhouse, Niranjan Y Sardesai, Ruxandra Draghia-Akli, David B Weiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2429965?pdf=render

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