Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin
Recent successes of adeno-associated virus (AAV)âbased gene therapy have created a demand for large-scale AAV vector manufacturing and purification techniques for use in clinical trials and beyond. During the development of purification protocols for rh.10, hu.37, AAV8, rh.64R1, AAV3B, and AAV9 vect...
Main Authors: | Qiang Wang, Martin Lock, Andrew J Prongay, Mauricio R Alvira, Boris Petkov, James M Wilson |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-01-01
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Series: | Molecular Therapy: Methods & Clinical Development |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2329050116300523 |
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