Localised release of matrix metallopeptidase 8 in fatal cerebral malaria

Localised release of matrix metallopeptidase 8 in fatal cerebral malaria

Abstract Objective Cerebral malaria (CM) is a complication of Plasmodium falciparum malaria, in which progressive brain swelling is associated with sequestration of parasites and impaired barrier function of the cerebral microvascular endothelium. To test the hypothesis that localised release of mat...

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Bibliographic Details
Main Authors: Athina Georgiadou, Praveena Naidu, Sophie Walsh, Steve Kamiza, Valentina Barrera, Simon P Harding, Christopher A Moxon, Aubrey J Cunnington
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Clinical & Translational Immunology
Subjects:
cerebral malaria
matrix metalloproteinase 8
neutrophils
pathogenesis
Online Access:https://doi.org/10.1002/cti2.1263

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