High epitope expression levels increase competition between T cells.

Both theoretical predictions and experimental findings suggest that T cell populations can compete with each other. There is some debate on whether T cells compete for aspecific stimuli, such as access to the surface on antigen-presenting cells (APCs) or for specific stimuli, such as their cognate e...

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Bibliographic Details
Main Authors: Almut Scherer, Marcel Salathé, Sebastian Bonhoeffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1550274?pdf=render