Growth Arrest-Specific Factor 6 (GAS6) Is Increased in COVID-19 Patients and Predicts Clinical Outcome

Growth Arrest-Specific Factor 6 (GAS6) Is Increased in COVID-19 Patients and Predicts Clinical Outcome

Background: Growth arrest-specific factor 6 (GAS6) and the Tyro3, AXL, and MERTK (TAM) receptors counterbalance pro-inflammatory responses. AXL is a candidate receptor for SARS-CoV-2, particularly in the respiratory system, and the GAS6/AXL axis is targeted in current clinical trials against COVID-1...

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Bibliographic Details
Main Authors: Albert Morales, Silvia Rojo Rello, Helena Cristóbal, Aida Fiz-López, Elisa Arribas, Montserrat Marí, Anna Tutusaus, Paloma de la Cal-Sabater, Gerry A.F. Nicolaes, José T. Ortiz-Pérez, David Bernardo, Pablo García de Frutos
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomedicines
Subjects:
COVID-19
AXL
MERTK
GAS6
viral infection
immune response
Online Access:https://www.mdpi.com/2227-9059/9/4/335

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