Upregulation of Glutamate Transporter 1 by Clavulanic Acid Administration and Attenuation of Allodynia and Hyperalgesia in Neuropathic Rats

Upregulation of Glutamate Transporter 1 by Clavulanic Acid Administration and Attenuation of Allodynia and Hyperalgesia in Neuropathic Rats

Introduction: Clavulanic acid (CLAV) is structurally similar to ceftriaxone, a potent stimulator of glial GlutamateTransporter-1 (GLT-1) expression. The present study aims at exploring the anti-nociceptive effects of CLAV, a beta-lactamase inhibitor in rats underwent sciatic nerve Chronic Constricti...

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Bibliographic Details
Main Authors: Bahareh Amin, Mahmoud Avaznia, Reihaneh Noorani, Soghra Mehri, Hossein Hosseinzadeh
Format: Article
Language:English
Published: Iran University of Medical Sciences 2019-07-01
Series:Basic and Clinical Neuroscience
Subjects:
clavulanic acid
chronic constriction injury
glutamate transporter 1
Online Access:http://bcn.iums.ac.ir/article-1-747-en.html

Internet

http://bcn.iums.ac.ir/article-1-747-en.html

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