Evaluation of the New Compression-Perimeter Test Effectiveness in the Early Diagnosis of Glaucoma

Purpose: To evaluate the effectiveness of a new modification of the vacuum-perimeter test (VPT) by V.V. Volkov in the early diagnosis of glaucoma in comparison with the results of the original test and its known modification — vacuum-compression automated test (VCAT) in an open comparative clinical...

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Main Authors: V. V. Volkov, I. L. Simakova, I. A. Tikhonovskaya
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2020-06-01
Series:Oftalʹmologiâ
Subjects:
Online Access:https://www.ophthalmojournal.com/opht/article/view/1201
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spelling doaj-04a40b7c43974577ace28cd8c10b68292021-07-29T08:55:29ZrusOphthalmology Publishing GroupOftalʹmologiâ 1816-50952020-06-0117222923710.18008/1816-5095-2020-2-229-237625Evaluation of the New Compression-Perimeter Test Effectiveness in the Early Diagnosis of GlaucomaV. V. Volkov0I. L. Simakova1I. A. Tikhonovskaya2Military Medical Academy named S.М. KirovMilitary Medical Academy named S.М. KirovMilitary Medical Academy named S.М. KirovPurpose: To evaluate the effectiveness of a new modification of the vacuum-perimeter test (VPT) by V.V. Volkov in the early diagnosis of glaucoma in comparison with the results of the original test and its known modification — vacuum-compression automated test (VCAT) in an open comparative clinical research. Patients and Methods. The study involved 26 patients (47 eyes) (average age 52.9 ± 8.5 years) with suspected open-angle glaucoma (OAG). Patients were divided into three groups: 1-st — 19 eyes with preglaucoma, 2-nd — 18 eyes with the early stage of OAG, 3-rd — 10 eyes of five patients with unconfirmed glaucoma. The control group (4-th) included 20 eyes of 10 healthy people (average age 56.4 ± 4.4 years). Along with the standard ophthalmological examination, all patients underwent perimetry on Humphrey Visual Field Analyzer II 745i (Germany-USA), our modification of Frequency Doubling Technology (FDT) perimetry, evaluation of the optic nerve head (ONH) on Heidelberg Retina Tomograph (HRT 3, Germany) and three stress tests: VPT, VCAT and our modification — vacuum-contrast-frequency test (VCFT). VCFT was created on the base of FDT perimetry with the aim of increasing the sensitivity of the original test (VPT) for detection of preglaucoma through the use of non-standard stimulus and increasing the number of investigated points of central visual field.  Results. According to the National classification (1975) the diagnosis of preglaucoma was determined on the basis of a positive result of at least one of three stress tests, taking into account the risk factors for the development of glaucoma in patients. The early stage of OAG was established on the base of International standards for structural and functional assessment of the ONH (2003). The specificity of all three compared stress tests was 100 %, which confirmed their negative results in all patients (10 eyes) from the 3-rd group. However, the sensitivity of VCFT (75 %) was significantly higher than VPT (21.05 %) and VCAT (21.05 %), which is due, we believe, to the specific nature of VCFT stimulus. Conclusion. According to the obtained data, the developed new modification of VPT — VCFT on the specificity of the results was not worse, and the sensitivity was better than the original VPT and VCAT in the diagnosis of preglaucoma. VCFT is quickly performed and comfortable for patients.https://www.ophthalmojournal.com/opht/article/view/1201early diagnosis of glaucomapreglaucomaopen-angle glaucomastress test
collection DOAJ
language Russian
format Article
sources DOAJ
author V. V. Volkov
I. L. Simakova
I. A. Tikhonovskaya
spellingShingle V. V. Volkov
I. L. Simakova
I. A. Tikhonovskaya
Evaluation of the New Compression-Perimeter Test Effectiveness in the Early Diagnosis of Glaucoma
Oftalʹmologiâ
early diagnosis of glaucoma
preglaucoma
open-angle glaucoma
stress test
author_facet V. V. Volkov
I. L. Simakova
I. A. Tikhonovskaya
author_sort V. V. Volkov
title Evaluation of the New Compression-Perimeter Test Effectiveness in the Early Diagnosis of Glaucoma
title_short Evaluation of the New Compression-Perimeter Test Effectiveness in the Early Diagnosis of Glaucoma
title_full Evaluation of the New Compression-Perimeter Test Effectiveness in the Early Diagnosis of Glaucoma
title_fullStr Evaluation of the New Compression-Perimeter Test Effectiveness in the Early Diagnosis of Glaucoma
title_full_unstemmed Evaluation of the New Compression-Perimeter Test Effectiveness in the Early Diagnosis of Glaucoma
title_sort evaluation of the new compression-perimeter test effectiveness in the early diagnosis of glaucoma
publisher Ophthalmology Publishing Group
series Oftalʹmologiâ
issn 1816-5095
publishDate 2020-06-01
description Purpose: To evaluate the effectiveness of a new modification of the vacuum-perimeter test (VPT) by V.V. Volkov in the early diagnosis of glaucoma in comparison with the results of the original test and its known modification — vacuum-compression automated test (VCAT) in an open comparative clinical research. Patients and Methods. The study involved 26 patients (47 eyes) (average age 52.9 ± 8.5 years) with suspected open-angle glaucoma (OAG). Patients were divided into three groups: 1-st — 19 eyes with preglaucoma, 2-nd — 18 eyes with the early stage of OAG, 3-rd — 10 eyes of five patients with unconfirmed glaucoma. The control group (4-th) included 20 eyes of 10 healthy people (average age 56.4 ± 4.4 years). Along with the standard ophthalmological examination, all patients underwent perimetry on Humphrey Visual Field Analyzer II 745i (Germany-USA), our modification of Frequency Doubling Technology (FDT) perimetry, evaluation of the optic nerve head (ONH) on Heidelberg Retina Tomograph (HRT 3, Germany) and three stress tests: VPT, VCAT and our modification — vacuum-contrast-frequency test (VCFT). VCFT was created on the base of FDT perimetry with the aim of increasing the sensitivity of the original test (VPT) for detection of preglaucoma through the use of non-standard stimulus and increasing the number of investigated points of central visual field.  Results. According to the National classification (1975) the diagnosis of preglaucoma was determined on the basis of a positive result of at least one of three stress tests, taking into account the risk factors for the development of glaucoma in patients. The early stage of OAG was established on the base of International standards for structural and functional assessment of the ONH (2003). The specificity of all three compared stress tests was 100 %, which confirmed their negative results in all patients (10 eyes) from the 3-rd group. However, the sensitivity of VCFT (75 %) was significantly higher than VPT (21.05 %) and VCAT (21.05 %), which is due, we believe, to the specific nature of VCFT stimulus. Conclusion. According to the obtained data, the developed new modification of VPT — VCFT on the specificity of the results was not worse, and the sensitivity was better than the original VPT and VCAT in the diagnosis of preglaucoma. VCFT is quickly performed and comfortable for patients.
topic early diagnosis of glaucoma
preglaucoma
open-angle glaucoma
stress test
url https://www.ophthalmojournal.com/opht/article/view/1201
work_keys_str_mv AT vvvolkov evaluationofthenewcompressionperimetertesteffectivenessintheearlydiagnosisofglaucoma
AT ilsimakova evaluationofthenewcompressionperimetertesteffectivenessintheearlydiagnosisofglaucoma
AT iatikhonovskaya evaluationofthenewcompressionperimetertesteffectivenessintheearlydiagnosisofglaucoma
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