Invasive Candida Infections in the ICU: Diagnosis and Therapy

Invasive fungal infections have become a serious problem in the critically ill. One of the main reasons is the development of an immunocompromised condition. The most frequently found pathogens are Candida species. In order to provide adequate treatment, understanding this potentially life-threateni...

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Bibliographic Details
Main Authors: Hankovszky Péter, Társy Domokos, Öveges Nándor, Molnár Zsolt
Format: Article
Language:English
Published: Sciendo 2015-10-01
Series:The Journal of Critical Care Medicine
Subjects:
Online Access:https://doi.org/10.1515/jccm-2015-0025
Description
Summary:Invasive fungal infections have become a serious problem in the critically ill. One of the main reasons is the development of an immunocompromised condition. The most frequently found pathogens are Candida species. In order to provide adequate treatment, understanding this potentially life-threatening infection is mandatory. The aim of this summary is to view Candida infections from a different perspective and to give an overview on epidemiology, the range of pathophysiology from colonization to the invasive infections, and its impact on mortality. New therapeutic options will also be discussed and how these relate to current guidelines. Finally, the key issue of the choice of antifungal agents will be evaluated.
ISSN:2393-1817